Table of Contents

Section i: basic principles.
Chapter 1: introduction: the nature of drugs & drug development & regulation.
Chapter 2: drug receptors & pharmacodynamics.
Chapter 3: pharmacokinetics & pharmacodynamics: rational dosing & the time course of drug action.
Chapter 4: drug biotransformation.
Chapter 5: pharmacogenomics.
Section ii: autonomic drugs.
Chapter 6: introduction to autonomic pharmacology.
Chapter 7: cholinoceptor-activating & cholinesterase-inhibiting drugs.
Chapter 8: cholinoceptor-blocking drugs.
Chapter 9: adrenoceptor agonists & sympathomimetic drugs.
Chapter 10: adrenoceptor antagonist drugs.
Section iii: cardiovascular-renal drugs.
Chapter 11: antihypertensive agents.
Chapter 12: vasodilators & the treatment of angina pectoris.
Chapter 13: drugs used in heart failure.
Chapter 14: agents used in cardiac arrhythmias.
Chapter 15: diuretic agents.
Section iv: drugs with important actions on smooth muscle.
Chapter 16: histamine, serotonin, & the ergot alkaloids.
Chapter 17: vasoactive peptides.
Chapter 18: the eicosanoids: prostaglandins, thromboxanes, leukotrienes, & related compounds.
Chapter 19: nitric oxide.
Chapter 20: drugs used in asthma.
Section v: drugs that act in the central nervous system.
Chapter 21: introduction to the pharmacology of cns drugs.
Chapter 22: sedative-hypnotic drugs.
Chapter 23: the alcohols.
Chapter 24: antiseizure drugs.
Chapter 25: general anesthetics.
Chapter 26: local anesthetics.
Chapter 27: skeletal muscle relaxants.
Chapter 28: pharmacologic management of parkinsonism & other movement disorders.
Chapter 29: antipsychotic agents & lithium.
Chapter 30: antidepressant agents.
Chapter 31: opioid agonists & antagonists.
Chapter 32: drugs of abuse.
Section vi: drugs used to treat diseases of the blood, inflammation, & gout.
Chapter 33: agents used in cytopenias; hematopoietic growth factors.
Chapter 34: drugs used in disorders of coagulation.
Chapter 35: agents used in dyslipidemia.
Chapter 36: nonsteroidal anti-inflammatory drugs, disease-modifying antirheumatic drugs, nonopioid analgesics, & drugs used in gout.
Section vii: endocrine drugs.
Chapter 37: hypothalamic & pituitary hormones.
Chapter 38: thyroid & antithyroid drugs.
Chapter 39: adrenocorticosteroids & adrenocortical antagonists.
Chapter 40: the gonadal hormones & inhibitors.
Chapter 41: pancreatic hormones & antidiabetic drugs.
Chapter 42: agents that affect bone mineral homeostasis.
Section viii: chemotherapeutic drugs.
Section viii: chemotherapeutic drugs: introduction.
Chapter 43: beta-lactam & other cell wall- & membrane-active antibiotics.
Chapter 44: tetracyclines, macrolides, clindamycin, chloramphenicol, streptogramins, & oxazolidinones.
Chapter 45: aminoglycosides & spectinomycin.
Chapter 46: sulfonamides, trimethoprim, & quinolones.
Chapter 47: antimycobacterial drugs.
Chapter 48: antifungal agents.
Chapter 49: antiviral agents.
Chapter 50: miscellaneous antimicrobial agents; disinfectants, antiseptics, & sterilants.
Chapter 51: clinical use of antimicrobial agents.
Chapter 52: antiprotozoal drugs.
Chapter 53: clinical pharmacology of the antihelminthic drugs.
Chapter 54: cancer chemotherapy.
Chapter 55: immunopharmacology.
Section ix: toxicology.
Chapter 56: introduction to toxicology: occupational & environmental.
Chapter 57: heavy metal intoxication & chelators.
Chapter 58: management of the poisoned patient.
Section x: special topics.
Chapter 59: special aspects of perinatal & pediatric pharmacology.
Chapter 60: special aspects of geriatric pharmacology.
Chapter 61: dermatologic pharmacology.
Chapter 62: drugs used in the treatment of gastrointestinal diseases.
Chapter 63: therapeutic & toxic potential of over-the-counter agents.
Chapter 64: dietary supplements & herbal medications.
Chapter 65: rational prescribing & prescription writing.
Chapter 66: important drug interactions & their mechanisms.
Appendix: vaccines, immune globulins, & other complex biologic products.