Table of Contents

Cover.
TOC$Contents.
Introduction.
CH$1. The Ethics of Aging Intervention and Life-Extension.
INTRODUCTION.
THE PROBLEM OF VALUE: LIFE-EXTENSION AND DEATH POSTPONING.
O Death, Where is Thy Sting?.
The Value of Living: Life-Extension and the Relative Badness of Death.
ARGUMENTS AGAINST BIOGERONTOLOGICAL INTERVENTION.
Natural Aging and Human Intervention.
Overpopulation and Sociobiological Reproductive Pressures.
Mythic Immortality vs. Life-Extension: Problems of Finitude, Striving, Boredom and Personal Identity.
The Problem of Incumbency and the Social Value of Life-Extension.
Problems of Unity: Distributive Justice, Parallel Populations, Parallel Species.
CONCLUSION.
REFERENCES.
CH$2. Prevention and Treatment of Skin Aging.
INTRODUCTION.
PREVENTION OF SKIN AGING.
Sunscreen.
Hormone Therapy.
TREATMENT OF SKIN AGING.
Topical Pharmaceuticals.
Surgical Interventions.
CONCLUSION.
REFERENCES.
CH$3. Industrial Approaches Towards Developing Effective Skin Care Products.
INTRODUCTION.
PROMINENT AGING THEORIES.
PHYSIOLOGICAL TARGETS IN ANTI-AGE PROPHYLAXIS AND TREATMENT.
ACTIVE COSMETIC INGREDIENTS AND THEIR POTENTIAL.
Moisturizers.
UV-FILTERS.
ANTIOXIDANTS.
Exfoliation.
Vitamin A and its Derivatives.
Coenzyme Q10 and Creatine.
Anti-inflammatory Actives.
FUTURE PERSPECTIVES.
REFERENCES.
CH$4. Strategies to Reduce Age-Related Skeletal Muscle Wasting.
INTRODUCTION.
UNDERLYING MECHANISMS OF AGE-RELATED CHANGES IN SKELETAL MUSCLE.
EXERCISE AND AGING.
Use it or Lose it? Exercise Alone Will Not Prevent Sarcopenia.
Innervation and Neurotrophic Factors.
Systemic Changes in Circulating Hormones and Other Factors.
Growth Hormone/IGF-I.
Treating Sarcopenia is not Simply 8220;Hormone Replacement Therapy8221;.
2-Adrenoceptor Agonists.
Risks and Benefits of Muscle Anabolic Therapies for Sarcopenia.
Myostatin.
Vitamin D.
Inflammatory Cytokines.
Metabolism, Energy Balance and Nutrition.
CONCLUSION.
ACKNOWLEDGMENTS.
REFERENCES.
CH$5. Antioxidants and Aging in Human Beings.
INTRODUCTION.
FREE RADICAL THEORY OF AGING AND THE USE OF ANTIOXIDANTS.
EFFECTS OF ANTIOXIDANTS ON AGING AND MORTALITY.
Circulating Antioxidants and Resistance to Free Radicals in Very Old People.
Antioxidants and Mortality.
Diet and Mortality.
Antioxidants and Aging.
Diet and Aging.
CONCLUSIONS.
REFERENCES.
CH$6. Hormone Therapy for Aging.
GROWTH HORMONE.
INSULIN.
MELATONIN.
DEHYDROEPIANDROSTERONE (DHEA).
ANDROGENS.
ESTROGENS.
HARMFUL EFFECTS OF HORMONAL THERAPY.
SUMMARY AND PROSPECTIVES.
ACKNOWLEDGMENTS.
REFERENCES.
CH$7. Pineal Peptides as Modulators of Aging.
INTRODUCTION.
PINEAL POLYPEPTIDE PREPARATION EPITHALAMIN.
EPITALON (ALAGLUASPGLY).
EFFECTS OF PINEAL PEPTIDES ON AGING IN HUMANS.
CONCLUSIONS.
REFERENCES.
CH$8. Melatonin: Anti-Aging Perception and Current Perspectives.
INTRODUCTION.
MELATONIN AND CIRCADIAN RHYTHM.
MELATONIN AND AGING.
ANTIOXIDATIVE NATURE OF MELATONIN.
MELATONIN AGAINST RADIATION DAMAGE.
DOSE DISCREPANCY.
MELATONIN AS AN ANTI-CARCINOGEN.
MELATONIN AGAINST DEPRESSIVE DISORDERS.
MEL This comprehensive volume surveys the molecular, cellular, hormonal, nutritional, medical, and lifestyle strategies being tested and applied for the prevention, intervention, and treatment of age-related diseases. With authoritative contributions not just from researchers in academic institutions and pharmaceutical and cosmeceutical industries, but also practicing clinicians of both mainstream and alternative medicine, demographers and bioethicists, this book provides unique scientific, ethical, and social perspectives on the discussion of aging intervention. In addition, the latest technologies in development, which will have serious bearings on future aging interventions, are reviewed. "Aging Interventions and Therapies" is ideal for graduates and undergraduates in universities and medical and nursing colleges, as well as post-graduates researching different aspects of aging and anti-aging. The topics covered are also highly relevant for professionals in the pharmaceutical, cosmeceutical, nutrition and healthcare industries, and practicing clinicians looking for a reliable and up-to-date resource on aging intervention and therapy.