Terkko Navigator / Aging

Exosome long non-coding RNA SOX2-OT contributes to ovarian cancer malignant progression by miR-181b-5p/SCD1 signaling

Hypoxic tubular epithelial cells regulate the angiogenesis of HMEC-1 cells via mediation of Rab7/MMP-2 axis

Profound synchrony of age-specific incidence rates and tumor suppression for different cancer types as revealed by the multistage-senescence model of carcinogenesis

Circular RNA circPRKCI contributes to malignant progression of T-cell acute lymphoblastic leukemia by modulating miR-20a-5p/SOX4 axis

Loganin substantially ameliorates molecular deficits, pathologies and cognitive impairment in a mouse model of Alzheimer's disease

AHNAK suppresses ovarian cancer progression through the Wnt/β-catenin signaling pathway

Selected ideal natural ligand against TNBC by inhibiting CDC20, using bioinformatics and molecular biology

Comprehensive analysis of prognostic genes in gastric cancer

Differences in and verification of genetic alterations in chemotherapy and immunotherapy for metastatic melanoma

Analysis of gut microbiota and metabolites in patients with rheumatoid arthritis and identification of potential biomarkers

ALDH2 promotes uterine corpus endometrial carcinoma proliferation and construction of clinical survival prognostic model

Differential expression of long non-coding RNAs as diagnostic markers for lung cancer and other malignant tumors

Adipokines, cell polarity disruption and breast cancer

A genetic determinant of VEGF-A levels is associated with telomere attrition

NEOage clocks - epigenetic clocks to estimate post-menstrual and postnatal age in preterm infants

A novel mutation in <em>PCK2</em> gene causes primary angle-closure glaucoma

Effects of Yu Linzhu on ovarian function and oocyte mitochondria in natural aging mice

Differential moderation effects of ApoE and 5-HTTLPR genotypes on social vulnerability in predicting mortality among community-dwelling middle-aged and older adults: a nationwide population-based study

Resveratrol promotes axonal regeneration after spinal cord injury through activating Wnt/β-catenin signaling pathway

piRNA-36741 regulates BMP2 mediated osteoblast differentiation via METTL3 controlled m6A modification

Potentiated lung adenocarcinoma (LUAD) cell growth, migration and invasion by lncRNA DARS-AS1 via miR-188-5p/ KLF12 axis

Cosmc transfection decreases malignant behavior of Tn⁺ cells and enhances sensitivity to apoptosis when induced by Apo2L/TRAIL via alteration of O-glycan structure

Nmnat2 attenuates amyloidogenesis and up-regulates ADAM10 in AMPK activity-dependent manner

Exposure to ionizing radiation disrupts normal epigenetic aging in Japanese medaka

Whole-exome sequencing of rectal cancer identifies locally recurrent mutations in the Wnt pathway

Transcriptome and proteome analysis of the antitumor activity of maslinic acid against pancreatic cancer cells

Immunological age prediction in HIV-infected, ART-treated individuals

The central role of the glutamate metabolism in long-term antiretroviral treated HIV-infected individuals with metabolic syndrome

Transcriptome research identifies four hub genes related to primary myelofibrosis: a holistic research by weighted gene co-expression network analysis

Integrated analysis of tumor-associated macrophage infiltration and prognosis in ovarian cancer

Identification of potential target genes of non-small cell lung cancer in response to resveratrol treatment by bioinformatics analysis

Long non-coding RNA CRNDE as potential biomarkers facilitate inflammation and apoptosis in alcoholic liver disease

Impact of aging on primary liver cancer: epidemiology, pathogenesis and therapeutics

Preventing metastatic emergence of breast cancer

Circulating CD5L is associated with cardiovascular events and all-cause mortality in individuals with chronic kidney disease

Network pharmacology for systematic understanding of Schisandrin B reduces the epithelial cells injury of colitis through regulating pyroptosis by AMPK/Nrf2/NLRP3 inflammasome

Neurovascular dysfunction and neuroinflammation in a Cockayne syndrome mouse model

Comprehensive analysis of aberrant alternative splicing related to carcinogenesis and prognosis of papillary thyroid cancer

Decreased gray matter volume and increased white matter volume in patients with neovascular age-related macular degeneration: a voxel-based morphometry study

Inhibition of JAK2/STAT3 signaling pathway by panaxadiol limits the progression of pancreatic cancer

Short-term high-fat diet favors the appearances of apoptosis and gliosis by activation of ERK1/2/p38MAPK pathways in brain

Ribosome profiling reveals translatome remodeling in cancer cells in response to zinc oxide nanoparticles

LncRNA-SNHG1 promotes macrophage M2-like polarization and contributes to breast cancer growth and metastasis

Iron: an underrated factor in aging

Low expression of endoplasmic reticulum stress-related gene SERP1 is associated with poor prognosis and immune infiltration in skin cutaneous melanoma

Zhoushi Qi Ling decoction represses docetaxel resistance and glycolysis of castration-resistant prostate cancer via regulation of SNHG10/miR-1271-5p/TRIM66 axis

METTL3 regulates hippocampal gene transcription via N6-methyladenosine methylation in sevoflurane-induced postoperative cognitive dysfunction mouse

A novel prognostic signature based on immune-related genes of diffuse large B-cell lymphoma

Establishment of a novel ferroptosis-related lncRNA pair prognostic model in colon adenocarcinoma

Agomelatine might be more appropriate for elderly depressed type 2 diabetes mellitus patients than paroxetine/fluoxetine