Table of Contents

Opportunity for efficiency.
Defining and extending the adaptive approach.
Design adaptations part one : finding the right dose.
Design adaptations part two : additional design changes.
Operational adaptations.
Agile clinical development.
Planning adaptive programs.
Statistics and decision making in adaptive research.
The agile platform.
The future of clinical development. Apply adaptive research to improve results in drug development. The pharmaceutical industry today faces a deepening crisis: inefficiency in its core business, the development of new drugs. The Agile Approach to Adaptive Research offers a solution. It outlines how adaptive research, using already-available tools and techniques, can enable the industry to streamline clinical trials and reach decision points faster and more efficiently. With a wealth of real-world cases and examples, author Michael Rosenberg gives readers a practical overview of drug development, the problems inherent in current.