Table of Contents

Anatomy and physiology of the knee.
Clinical presentation and natural history of osteoarthritis.
Clinical radiographic diagnosis for osteoarthritis of the knee.
Introduction to magnetic resonance imaging.
Current magnetic resonance imaging techniques for clinical diagnosis and staging of knee osteoarthritis.
Quantitative morphological imaging of the knee joint.
Functional imaging of the knee joint.
Bone and osteoarthritis. Osteoarthritis is a condition in which low-grade inflammation results in joint pain, and it is the most common joint disease. Interactions between all of the major joint tissues, including the articular cartilage, synovium, bone marrow, subchondral bone, trabecular bone, and muscle, have been implicated in osteoarthritis. Magnetic resonance images have been used to quantify the cartilage morphology, volume and thickness, and focal defects, and may reflect changes in the biochemical composition of articular cartilage. This book brings together contributions from key investigators in the area of