Table of Contents

Cover image; Title page; Table of Contents; Copyright; Contributors; Preface; Chapter One: The Mechanistic Complexities of Phycotoxins: Toxicology of Azaspiracids and Yessotoxins; Abstract; 1 Introduction; 2 Azaspiracids; 3 Yessotoxins; Acknowledgments; Chapter Two: Advances in the Analysis of Challenging Food Contaminants: Nanoparticles, Bisphenols, Mycotoxins, and Brominated Flame Retardants; Abstract; 1 Introduction; 2 Analytical Methodology for the Analysis of Nanoparticles; 3 Analytical Methodology for the Analysis of Bisphenols; 4 Analytical Methodology for the Analysis of Mycotoxins 3 Drug-DNA Interaction: "Inhibitor Versus Poison"4 Topoisomerase Inhibitors in Cancer Therapy; 5 Secondary Plant Constituents as Topoisomerase Inhibitors; 6 Conclusion; Acknowledgments; Chapter Five: Toxicity of Plasmonic Nanomaterials and Their Hybrid Nanocomposites; Abstract; 1 Introduction; 2 Toxicity Testing and Risk Assessment of Nanomaterials; 3 Toxicity Evaluation; 4 Animal Testing for Toxicity; 5 Factors Affecting Nanotoxicology; 6 Genotoxicology; 7 The Most Common Genotoxicological Tests; 8 Genotoxicity of Plasmonic Nanomaterials 5 Analytical Methodology for the Analysis of BFRs6 Conclusions; Acknowledgments; Chapter Three: Mycotoxins from Alternaria: Toxicological Implications; Abstract; 1 Introduction; 2 Chemical Structures; 3 Acute Toxicity; 4 Toxicokinetics and Metabolism; 5 Genotoxicity and Related Mechanism; 6 Estrogenic Activity and Related Mechanisms; 7 Mutagenicity and Carcinogenicity; 8 Gastrointestinal Stability of AOH and ALT Under In Vitro Human Conditions; 9 Conclusions and Outlook; Chapter Four: Food-Borne Topoisomerase Inhibitors: Risk or Benefit; Abstract; 1 Introduction; 2 Catalytic Enzyme Cycle 9 Evaluation of Genotoxicity of Magneto-Plasmonic Hybrid Nanocomposites10 Conclusion; Chapter Six: Aluminum Phytotoxicity: Physiological Approaches and Tolerance; Abstract; 1 General Considerations; 2 Aluminum and Plants' Responses; 3 Aluminum and the Apoplast-Symplast Continuum; 4 Aluminum and Oxidative Stress; 5 Aluminum and Callose Deposition; 6 Aluminum and Photosynthesis; 7 Aluminum Tolerance; 8 Final Remarks; Acknowledgments; Index Advances in Molecular Toxicology features the latest advances in all of the subspecialties of the broad area of molecular toxicology. Toxicology is the study of poisons, and this series details the study of the molecular basis by which a vast array of agents encountered in the human environment and produced by the human body itself manifest themselves as toxins. Not strictly limited to documenting these examples, the series is also concerned with the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnesse.