Table of Contents

Front Matter.
HCV Replication / Michael R Beard.
Hepatitis C Virus Genotypes / Scott A Read, Mark W Douglas.
Immune Responses to HCV: Implications for Therapy / David G Bowen.
Mechanisms of Action of Antiviral Drugs: The Interferons / Edmund Tse, Michael R Beard.
Pharmacology and Mechanisms of Action of Antiviral Drugs: Ribavirin Analogs / Fred Poordad, Grace M Chee.
Pharmacology and Mechanisms of Action of Antiviral Drugs: Polymerase Inhibitors / Lotte Coelmont, Leen Delang, Mathy Froeyen, Piet Herdewijn, Johan Neyts.
Pharmacology and Mechanisms of Action of Antiviral Drugs: Protease Inhibitors / Laurent Chatel-Chaix, Martin Baril, Daniel Lamarre.
Measuring Antiviral Responses / Jean-Michel Pawlotsky, Sťphane Chevaliez.
Genotype 1: Standard Treatment / Rebekah G Gross, Ira M Jacobson.
Individually Tailored Treatment Strategies in Treatment-na̐ve Chronic Hepatitis C Genotype 1 Patients / Johannes Wiegand, Thomas Berg.
Genotype 1 Relapsers and Non-Responders / Salvatore Petta, Antonio Crax.
Standard Therapy for Genotypes 2/3 / Kenneth Yan, Amany Zekry.
Altered Dosage or Durations of Current Antiviral Therapy for HCV Genotypes 2 and 3 / Alessandra Mangia, Leonardo Mottola, Angelo Andriulli.
Genotypes 2 and 3 Relapse and Non-Response / Stella Mart̕nez, Jose Mar̕a S̀nchez-Tapias, Xavier Forns.
Hepatitis C Genotype 4 Therapy: Progress and Challenges / Sanaa M Kamal.
Antivirals in Acute Hepatitis C / Heiner Wedemeyer.
Antivirals in Cirrhosis and Portal Hypertension / Diarmuid S Manning, Nezam H Afdhal.
Treatment of Recurrent Hepatitis C Following Liver Transplantation / Ed Gane.
Antiviral Treatment in Chronic Hepatitis C Virus Infection with Extrahepatic Manifestations / Benjamin Terrier, Patrice Cacoub.
Cytopenias: How they Limit Therapy and Potential Correction / Mitchell L Shiffman.
The Problem of Insulin Resistance and its Effect on Therapy / Venessa Pattullo, Jacob George.
HIV and Hepatitis C Co-Infection / Gail V Matthews, Gregory J Dore.
HCV and Racial Differences / Andrew J Muir.
HCV and the Pediatric Population / Kathleen B Schwarz.
New Horizons: IL28, Direct-Acting Antiviral Therapy for HCV / Alexander J Thompson, John G McHutchison, Geoffrey W McCaughan.
Index. According to the WHO, 170 million people, or 3% of the world's population, are infected with Hepatitis C and at risk of developing liver cirrhosis and/or liver cancer. 3-4 million people each year are newly diagnosed carriers of the virus. Advanced Therapy for Hepatitis C Infection provides you with expert guidance from the world's leading hepatologists on the very latest treatment options for patients with the HCV virus. Edited by a team of outstanding international reputation, Advanced Therapy for Hepatitis C Infection is an essential tool for all hepatologists and gastroenterologists involved in the management of patients with Hepatitis C.