- NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane391 days agoRead
- Small Molecule Destabilizer ofβ-Catenin and Ras Proteins Antagonizes Growth of K-Ras Mutation-Driven Colorectal Cancers Resistant to EGFR Inhibitors628 days agoRead
- Ras Diffusion and Interactions with the Plasma Membrane Measured by FRAP Variations411 days agoRead
- Novel regulation of Ras proteins by direct tyrosine phosphorylation and dephosphorylation649 days agoRead
- Cancers, Vol. 12, Pages 3326: Proximal Protein Interaction Landscape of RAS Paralogs594 days agoRead
- Cancers, Vol. 12, Pages 3326: Proximal Protein Interaction Landscape of RAS Paralogs593 days agoRead
- Biomolecules, Vol. 10, Pages 1535: Natural Products Attenuating Biosynthesis, Processing, and Activity of Ras Oncoproteins: State of the Art and Future Perspectives594 days agoRead
- Biomolecules, Vol. 10, Pages 1535: Natural Products Attenuating Biosynthesis, Processing, and Activity of Ras Oncoproteins: State of the Art and Future Perspectives594 days agoRead
- An expanded classification of active, inactive, and druggable RAS conformations142 days agoRead
- RAS and PP2A activities converge on epigenetic gene regulation46 days agoRead
- Genes, Vol. 12, Pages 1094: The Importance of Being PI3K in the RAS Signaling Network343 days agoRead
- Validation of a small molecule inhibitor of PDE6D-RAS interaction with potent anti-leukemic effects105 days agoRead
- CSIG-02. R-RAS SUBFAMILY PROTEINS ELICIT DISTINCT PHYSIOLOGIC EFFECTS AND PHOSPHOPROTEOME ALTERATIONS IN NEUROFIBROMIN-NULL MPNST CELLS595 days agoRead
- Promising Molecular Targets for Design of Antitumor Drugs Based on Ras Protein Signaling Cascades545 days agoRead
- Molecular Dynamics Simulation of Lipid-Modified Signaling Proteins338 days agoRead
- Cell-permeable CaaX-peptides affect K-Ras downstream signaling and promote cell death in cancer cells.606 days agoRead
- Inhibiting the "Undruggable" RAS/Farnesyltransferase (FTase) Cancer Target by Manumycin-related Natural Products425 days agoRead
- Using BioID to Characterize the RAS Interactome411 days agoRead
- Analysis of the H-Ras mobility pattern in vivo shows cellular heterogeneity inside epidermal tissue370 days agoRead
- Long-lasting Salt Bridges Provide the Anchoring Mechanism of Oncogenic Kirsten Rat Sarcoma Proteins at Cell Membranes.593 days agoRead
- Ras GEF Mouse Models for the Analysis of Ras Biology and Signaling411 days agoRead
- IJMS, Vol. 23, Pages 3706: Small-Molecule RAS Inhibitors as Anticancer Agents: Discovery, Development, and Mechanistic Studies91 days agoRead
- NMR in integrated biophysical drug discovery for RAS: past, present, and future679 days agoRead
- RAS GTPase signalling to alternative effector pathways.604 days agoRead
- Genes, Vol. 12, Pages 662: The Role of Wild-Type RAS in Oncogenic RAS Transformation425 days agoRead
- RASless MEFs as a Tool to Study RAS-Dependent and RAS-Independent Functions411 days agoRead
- Inhibition of mutant RAS-RAF interaction by mimicking structural and dynamic properties of phosphorylated RAS64 days agoRead
- Binding of Ras to Phosphoinositide 3-Kinase p110alpha Is Required for Ras- Driven Tumorigenesis in Mice.5504 days agoRead
- The R-Ras/RIN2/Rab5 complex controls endothelial cell adhesion and morphogenesis via active integrin endocytosis and Rac signaling.3619 days agoRead
- High-Throughput Dual Screening method for Ras Activities and Inhibitors.1924 days agoRead
- High-Throughput Dual Screening Method for Ras Activities and Inhibitors.1234 days agoRead
- Dynamically encoded reactivity of Ras enzymes: opening new frontiers for drug discovery677 days agoRead
- Oncogenic Ras disrupts epithelial integrity by activating the transmembrane serine protease hepsin.523 days agoRead
- Oncogenic Ras disrupts epithelial integrity by activating the transmembrane serine protease hepsin.523 days agoRead
- Oncogenic Ras disrupts epithelial integrity by activating the transmembrane serine protease hepsin.522 days agoRead
- Oncogenic Ras disrupts epithelial integrity by activating the transmembrane serine protease hepsin.522 days agoRead
- Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin425 days agoRead
- Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin425 days agoRead
- High-Throughput Dual Screening Method for Ras Activities and Inhibitors425 days agoRead
- Probing RAS Function with Monobodies411 days agoRead
- FLIM-FRET Analysis of Ras Nanoclustering and Membrane-Anchorage411 days agoRead
- Super-Resolution Imaging and Spatial Analysis of RAS on Intact Plasma Membrane Sheets411 days agoRead
- Ras isoform-specific expression, chromatin accessibility, and signaling331 days agoRead
- RAS mutation patterns arise from tissue-specific responses to distinct oncogenic signaling199 days agoRead
- Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin105 days agoRead
- Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin49 days agoRead
- Genes, Vol. 12, Pages 819: The Crossroads between RAS and RHO Signaling Pathways in Cellular Transformation, Motility and Contraction396 days agoRead
- Cancers, Vol. 12, Pages 3143: A Gene Expression High-Throughput Screen (GE-HTS) for Coordinated Detection of Functionally Similar Effectors in Cancer608 days agoRead
- Validation of Isoform- and Mutation-Specific RAS Antibodies411 days agoRead
- Horizontal gene transfers and cell fusions in microbiology, immunology and oncology (Review).4715 days agoRead
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