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An open source plant kinase chemogenomics set

Cells transformed by ODC, c-Ha-ras and v-src exhibit MAP kinase/Erk-independent constitutive phosphorylation of Sos, Raf and c-Jun activation domain, and reduced PDGF receptor expression

Genes, Vol. 11, Pages 1342: Emerging BRAF Mutations in Cancer Progression and Their Possible Effects on Transcriptional Networks

IJMS, Vol. 23, Pages 1548: Oncogenic Mutation BRAF V600E Changes Phenotypic Behavior of THLE-2 Liver Cells through Alteration of Gene Expression

Cardiomyocyte BRAF and type 1 RAF inhibitors promote cardiomyocyte and cardiac hypertrophy in mice in vivo

IJMS, Vol. 22, Pages 9151: Establishment of Canine Transitional Cell Carcinoma Cell Lines Harboring BRAF V595E Mutation as a Therapeutic Target

Ibrutinib Blocks YAP1 Activation and Reverses BRAF Inhibitor Resistance in Melanoma Cells [Articles]

Negative feedback by conserved kinases patterns degradation of C. elegans Raf in vulval fate patterning.

Circulating Tumor DNA Genomics Reveal Potential Mechanisms of Resistance to BRAF-Targeted Therapies in Patients with BRAF-Mutant Metastatic Non-Small Cell Lung Cancer

The Interplay between HGF/c-met Axis and Nox4 in BRAF Mutated Melanoma.

Inhibiting USP8 overcomes hepatocellular carcinoma resistance via suppressing receptor tyrosine kinases

2-Anilinoquinoline based arylamides as broad spectrum anticancer agents with B-RAFV600E/C-RAF kinase inhibitory effects: Design, synthesis, in vitro cell-based and oncogenic kinase assessments.

Mutation-oriented profiling of autoinhibitory kinase conformations predicts RAF inhibitor efficacies [Biochemistry]

JCM, Vol. 10, Pages 62: Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma

Intra-Cellular Calcium Signaling Pathways (PKC, RAS/RAF/MAPK, PI3K) in Lamina Cribrosa Cells in Glaucoma.

HIV-1 Nef-Induced Secretion of the Proinflammatory Protease TACE into Extracellular Vesicles Is Mediated by Raf-1 and Can Be Suppressed by Clinical Protein Kinase Inhibitors

Structure of the SHOC2-MRAS-PP1C complex provides insights into RAF activation and Noonan syndrome

MDM2 induces EMT via the B‑Raf signaling pathway through 14‑3‑3

A Clinical Evaluation of Circulating MiR-106a and Raf-1 as Breast Cancer Diagnostic and Prognostic Markers

Targeting Mutant Kirsten Rat Sarcoma Viral Oncogene Homolog in Non-Small Cell Lung Cancer: Current Difficulties, Integrative Treatments and Future Perspectives

Light-Regulated allosteric switch enables temporal and subcellular control of enzyme activity.

Cancers, Vol. 12, Pages 2936: The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells

Cancers, Vol. 12, Pages 2936: The In Vitro and In Vivo Anticancer Properties of Chalcone Flavokawain B through Induction of ROS-Mediated Apoptotic and Autophagic Cell Death in Human Melanoma Cells

Treatment exceeds expectations with vemurafenib monotherapy in a patient with BRAFV600E-mutant metastatic melanoma

Unbiased High-Throughput Drug Combination Pilot Screening Identifies Synergistic Drug Combinations Effective against Patient-Derived and Drug-Resistant Melanoma Cell Lines

Unbiased High-Throughput Drug Combination Pilot Screening Identifies Synergistic Drug Combinations Effective against Patient-Derived and Drug-Resistant Melanoma Cell Lines

Capitalizing on paradoxical activation of the MAPK pathway for treatment of Imatinib-resistant mast cell leukemia and chronic myelogenous leukemia

E3 ubiquitin ligase PARK2, an inhibitor of melanoma cell growth, is repressed by the oncogenic ERK1/2-ELK1 transcriptional axis [Signal Transduction]

LGG-46. MOLECULAR CHARACTERIZATION OF HEMISPHERIC LOW-GRADE GLIOMAS IN CHILDREN

Cells, Vol. 10, Pages 2509: ERK: A Double-Edged Sword in Cancer. ERK-Dependent Apoptosis as a Potential Therapeutic Strategy for Cancer

Gene expression profiles and signaling mechanisms inα2B-adrenoceptor-evoked proliferation of vascular smooth muscle cells.

Gene expression profiles and signaling mechanisms inα_2B-adrenoceptor-evoked proliferation of vascular smooth muscle cells

Inactivation of the Hippo Tumor Suppressor Pathway Promotes Melanoma

Characterization of Kinase Expression Related to Increased Migration of PC-3M Cells Using Global Comparative Phosphoproteome Analysis

Recent Understanding and Future Directions of Recurrent Corticotroph Tumors

A loss-of-function genetic screening identifies novel mediators of thyroid cancer cell viability.

MAPK- and AKT-activated thyroid cancers are sensitive to group I PAK inhibition.

Ibuprofen disrupts a WNK1/GSK3β/SRPK1 protein complex required for expression of tumor-related splicing variant RAC1B in colorectal cells.

Biomolecules, Vol. 11, Pages 777: Oximes: Novel Therapeutics with Anticancer and Anti-Inflammatory Potential

Characterization and clustering of kinase isoform expression in metastatic melanoma

Cancers, Vol. 14, Pages 1575: Identification of New Vulnerabilities in Conjunctival Melanoma Using Image-Based High Content Drug Screening

Characterization and clustering of kinase isoform expression in metastatic melanoma

Sorafenib as third- or fourth-line treatment of advanced gastrointestinal stromal tumour and pretreatment including both imatinib and sunitinib, and nilotinib: A retrospective analysis.

Biomedicines, Vol. 8, Pages 333: Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells

Withanolide Metabolites Inhibit PI3K/AKT and MAPK Pro-Survival Pathways and Induce Apoptosis in Acute Myeloid Leukemia Cells.

Transcriptome-wide identification of MAPKKK genes in bermudagrass (Cynodon dactylon L.) and their potential roles in low temperature stress responses

Molecules, Vol. 25, Pages 5192: Antiglioma Potential of Coumarins Combined with Sorafenib

Biomedicines, Vol. 9, Pages 726: RSK Isoforms in Acute Myeloid Leukemia

Mutated Ephrin Receptor Genes in Non-Small Cell Lung Carcinoma and Their Occurrence with Driver Mutations-Targeted Resequencing Study on Formalin-Fixed, Paraffin-Embedded Tumor Material of 81 Patients.

Mutated Ephrin Receptor Genes in Non-Small Cell Lung Carcinoma and Their Occurrence with Driver Mutations-Targeted Resequencing Study on Formalin-Fixed, Paraffin-Embedded Tumor Material of 81 Patients.