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Targetingβ1-integrin inhibits vascular leakage in endotoxemia

Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization

Integrated data analysis reveals uterine leiomyoma subtypes with distinct driver pathways and biomarkers

Mechanistic principles underlying regulation of the actin cytoskeleton by phosphoinositides

Distance to health services affects local-level vaccine efficacy for pneumococcal conjugate vaccine (PCV) among rural Filipino children

Redox-coupled quinone dynamics in the respiratory complex I

Understanding the essential proton-pumping kinetic gates and decoupling mutations in cytochrome <em>c</em> oxidase

Multiscale simulations reveal key features of the proton-pumping mechanism in cytochrome c oxidase

Redox-induced activation of the proton pump in the respiratory complex I

Proton-coupled electron transfer and the role of water molecules in proton pumping by cytochrome c oxidase

Electrostatics, hydration, and proton transfer dynamics in the membrane domain of respiratory complex I

Functional screen reveals SARS coronavirus nonstructural protein nsp14 as a novel cap N7 methyltransferase

Human population dynamics in Europe over the Last Glacial Maximum

Worldwide data sets constrain the water vapor uptake coefficient in cloud formation

Primer retention owing to the absence of RNase H1 is catastrophic for mitochondrial DNA replication

Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I

Synergistic effects of treating the spinal cord and brain in CLN1 disease

Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability

Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement

BCL2 regulates neural differentiation

Tumor suppressor function of Liver kinase B1 (Lkb1) is linked to regulation of epithelial integrity

Suppression of oncogenic properties of c-Myc by LKB1-controlled epithelial organization

Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis

Different opinion on the reported role of Poldip2 and ACSM1 in a mammalian lipoic acid salvage pathway controlling HIF-1 activation

Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

RhoA knockout fibroblasts lose tumor-inhibitory capacity in vitro and promote tumor growth in vivo

FGF receptor-4 (FGFR4) polymorphism acts as an activity switch of a membrane type 1 matrix metalloproteinase-FGFR4 complex

A tick-borne segmented RNA virus contains genome segments derived from unsegmented viral ancestors

Bone marrow-derived circulating endothelial precursors do not contribute to vascular endothelium and are not needed for tumor growth

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Synchronous down-modulation of miR-17 family members is an early causative event in the retinal angiogenic switch

Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors

Age-related memory impairment associated with loss of parietal deactivation but preserved hippocampal activation

Host genetic control of natural killer cell diversity revealed in the Collaborative Cross

Coupling between dynamic 3D tissue architecture and BMP morphogen signaling during <em>Drosophila</em> wing morphogenesis

The Drosophila DPP signal is produced by cleavage of its proprotein at evolutionary diversified furin-recognition sites

Traffic is a major source of atmospheric nanocluster aerosol

Modeling SHH-driven medulloblastoma with patient iPS cell-derived neural stem cells

Enhanced expression of MycN/CIP2A drives neural crest toward a neural stem cell-like fate: Implications for priming of neuroblastoma

VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection

Oaks adapt drought resistance to local conditions

Journal Club for February 2021: Deformation, instability, and assembly of materials by dynamic solid-liquid interactions

Researchers Develop Mathematical Model to Explain Complex Architecture of Termite Mounds; "Termite Mounds Are Amongst the Greatest Examples of Animal Architecture on Our Planet"

Machine-learning-driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis

Machine-learning-driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis

Single-molecule nanopore sequencing reveals extreme target copy number heterogeneity in arylomycin-resistant mutants

Life-long in vivo cell-lineage tracing shows that no oogenesis originates from putative germline stem cells in adult mice

Neuronal long-range temporal correlations and avalanche dynamics are correlated with behavioral scaling laws

Neuronal synchrony reveals working memory networks and predicts individual memory capacity